How to Quit Taking Nexium

Nexium (generic name: esomeprazole magnesium), the well-known purple pill from AstraZeneca, is a prescription medicine that usually requires a single dose each day to prevent heartburn and damage from acid reflux disease. In 2008, U.S. consumers spent $4.8 billion on Nexium---second only to Lipitor in brand-name prescription drug sales by dollar, according to Drug Topics magazine.

Side effects of Nexium may include headache, diarrhea and abdominal pain. You may have decided to stop taking this medication because of the side effects.

Instructions

1

Talk to your doctor before discontinuing Nexium. You should never stop or cut down the dosage of any prescription medication without informing the physician who prescribed it. Tell the doctor you intend to stop taking Nexium and why; perhaps there is another drug she can recommend that will be better suited for you. Your doctor will be aware of complications from acid reflux, such as esophageal damage, that may also need to be addressed.

2

Understand the possibility of "acid rebound." According to a study in a 1999 issue of the journal Gastroenterology, ceasing treatment with omeprazole (another PPI, or proton pump inhibitor, like Nexium) causes rebound acid secretion. In other words, the heartburn and other acid reflux problems will return, and may even be worse than before treatment. This has recently been confirmed in the July 2009 issue of the journal, which found that rebound acid hypersecretion is found after eight weeks of using a PPI, which can lead to dependence on the drug to avoid symptoms. Cope with this rebound effect with over-the-counter antacids; over-the-counter histamine2-receptor blockers such as cimetidine (Tagamet), famotidine (Pepcid) and ranitidine (Zantac); by avoiding foods known to trigger reflux (acidic juices, coffee, chocolate, high-fat foods) and eating properly; chewing gum; elevating the head of your bed; and drinking plenty of water.

3

Be patient. The 2009 Gastroenterology study scientists report that the PPI rebound effect lasts between one and three months. Be especially careful about your diet during this period to avoid acid damage, and keep your doctor apprised of your condition, particularly if your symptoms worsen.